Cohesive versus Flexible Evolution of Functional Modules in Eukaryotes
نویسندگان
چکیده
منابع مشابه
Cohesive versus Flexible Evolution of Functional Modules in Eukaryotes
Although functionally related proteins can be reliably predicted from phylogenetic profiles, many functional modules do not seem to evolve cohesively according to case studies and systematic analyses in prokaryotes. In this study we quantify the extent of evolutionary cohesiveness of functional modules in eukaryotes and probe the biological and methodological factors influencing our estimates. ...
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ژورنال
عنوان ژورنال: PLoS Computational Biology
سال: 2009
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1000276